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TriadP23201 protein (Trichoplax adhaerens) - STRING interaction network
"TriadP23201" - DNA topoisomerase 2 in Trichoplax adhaerens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
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[Homology]
Score
TriadP23201DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1164 aa)    
Predicted Functional Partners:
TriadP30199
annotation not available (560 aa)
     
 
  0.982
TriadP60794
Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes (705 aa)
     
 
  0.956
TriadP50834
annotation not available (200 aa)
   
 
  0.949
TriadP64300
annotation not available (1038 aa)
   
 
  0.933
TriadP30770
annotation not available (752 aa)
   
 
  0.929
TriadP22834
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (625 aa)
     
 
  0.899
TriadP55283
annotation not available (301 aa)
     
 
  0.886
TriadP19118
annotation not available (714 aa)
     
   
  0.868
TriadP32599
annotation not available (870 aa)
     
 
  0.866
TriadP50536
annotation not available (833 aa)
     
   
  0.861
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: T. adhaerens, Trichoplax adhaerens
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