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TriadP33826 protein (Trichoplax adhaerens) - STRING interaction network
"TriadP33826" - Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial in Trichoplax adhaerens
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TriadP33826Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6 (465 aa)    
Predicted Functional Partners:
TriadP20328
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2) (296 aa)
     
  0.993
TriadP61065
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family (302 aa)
 
 
  0.969
TriadP24662
5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner (196 aa)
 
 
 
  0.968
TriadP25833
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate (318 aa)
   
   
  0.951
TriadP5066
annotation not available (175 aa)
     
 
  0.949
TriadP26675
annotation not available (448 aa)
     
 
  0.941
TriadP20604
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family (264 aa)
     
 
  0.939
TriadP20625
annotation not available (302 aa)
   
 
  0.937
TriadP22596
annotation not available (153 aa)
           
  0.924
TriadP24469
annotation not available (454 aa)
   
 
  0.865
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: T. adhaerens, Trichoplax adhaerens
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