Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Groups of genes that are frequently observed in each other's genomic neighborhood.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
annotation not available (327 aa)
Predicted Functional Partners:
annotation not available (1101 aa)
annotation not available (633 aa)
annotation not available (1526 aa)
annotation not available (201 aa)
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (928 aa)
annotation not available (856 aa)
annotation not available (370 aa)
annotation not available (144 aa)
annotation not available (124 aa)
annotation not available (325 aa)
Your Current Organism:
NCBI taxonomy Id: 10228 Other names: T. adhaerens, Trichoplax adhaerens