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TriadP53360 protein (Trichoplax adhaerens) - STRING interaction network
"TriadP53360" - Ubiquitin-related modifier 1 homolog in Trichoplax adhaerens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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TriadP53360Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress sp [...] (122 aa)    
Predicted Functional Partners:
TriadP50356
annotation not available (360 aa)
     
  0.992
TriadP26003
annotation not available (653 aa)
     
   
  0.936
TriadP30260
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (349 aa)
     
 
  0.935
TriadP55610
Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (456 aa)
     
 
  0.931
TriadP50365
annotation not available (727 aa)
     
   
  0.889
TriadP63410
Ubiquitin-fold modifier 1; Ubiquitin-like modifier (92 aa)
     
   
  0.864
TriadP50199
annotation not available (77 aa)
     
   
  0.859
TriadP25845
annotation not available (442 aa)
       
 
  0.857
TriadP50528
Elongator complex protein 3; Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (515 aa)
     
 
  0.850
TriadP18881
annotation not available (409 aa)
     
   
  0.847
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: T. adhaerens, Trichoplax adhaerens
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