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TriadP55610 protein (Trichoplax adhaerens) - STRING interaction network
"TriadP55610" - Cytoplasmic tRNA 2-thiolation protein 2 in Trichoplax adhaerens
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TriadP55610Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (456 aa)    
Predicted Functional Partners:
TriadP30260
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (349 aa)
     
  0.996
TriadP26003
annotation not available (653 aa)
     
   
  0.939
TriadP53360
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress sp [...] (122 aa)
     
 
  0.931
TriadP50356
annotation not available (360 aa)
     
 
  0.931
TriadP59846
annotation not available (882 aa)
     
 
  0.908
TriadP18881
annotation not available (409 aa)
           
  0.906
TriadP50365
annotation not available (727 aa)
     
   
  0.848
TriadP55003
annotation not available (768 aa)
     
   
  0.837
TriadP50528
Elongator complex protein 3; Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (515 aa)
     
 
  0.729
TriadP52665
annotation not available (124 aa)
     
   
  0.727
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: T. adhaerens, Trichoplax adhaerens
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