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TriadP56013 protein (Trichoplax adhaerens) - STRING interaction network
"TriadP56013" - Putative uncharacterized protein in Trichoplax adhaerens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TriadP56013Putative uncharacterized protein (1020 aa)    
Predicted Functional Partners:
TriadP54713
Putative uncharacterized protein (1095 aa)
     
  0.958
TriadP54712
Predicted protein (1281 aa)
     
  0.949
TriadP52181
Putative uncharacterized protein (231 aa)
     
  0.944
TriadP23201
DNA topoisomerase 2 ; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1164 aa)
   
  0.943
TriadP26121
Putative uncharacterized protein (326 aa)
   
  0.940
TriadP22834
DNA topoisomerase ; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (625 aa)
   
  0.937
TriadP50671
Putative uncharacterized protein (556 aa)
     
  0.930
TriadP61244
Putative uncharacterized protein (480 aa)
     
  0.930
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (377 aa)
   
  0.926
TriadP49643
DNA topoisomerase ; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (841 aa)
   
  0.925
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: Placozoa, T. adhaerens, Trichoplax, Trichoplax adhaerens, placozoan, placozoans
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