• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
TriadP58651 protein (Trichoplax adhaerens) - STRING interaction network
"TriadP58651" - Uracil-DNA glycosylase in Trichoplax adhaerens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TriadP58651Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (276 aa)    
Predicted Functional Partners:
TriadP24211
annotation not available (157 aa)
   
 
  0.973
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (377 aa)
   
   
  0.927
TriadP34086
annotation not available (707 aa)
     
   
  0.921
TriadP33687
Uncharacterized protein; Component of the post-replicative DNA mismatch repair system (MMR) (984 aa)
     
 
  0.904
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family (292 aa)
   
 
  0.902
TriadP18453
annotation not available (317 aa)
   
 
  0.896
TriadP50695
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (261 aa)
   
 
  0.894
TriadP21078
annotation not available (382 aa)
   
 
  0.894
TriadP5178
annotation not available (308 aa)
     
   
  0.877
TriadP19413
annotation not available (527 aa)
   
 
  0.863
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: T. adhaerens, Trichoplax adhaerens
Server load: low (13%) [HD]