node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frr | pyrH | HLPCO_000121 | HLPCO_000120 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.998 |
frr | rplA | HLPCO_000121 | HLPCO_001385 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.963 |
frr | rplK | HLPCO_000121 | HLPCO_001386 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.952 |
frr | rplM | HLPCO_000121 | HLPCO_001300 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.964 |
frr | rplO | HLPCO_000121 | HLPCO_001355 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.954 |
frr | rplP | HLPCO_000121 | HLPCO_001367 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.956 |
frr | rplQ | HLPCO_000121 | HLPCO_001346 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L17. | 0.957 |
frr | rplT | HLPCO_000121 | HLPCO_000611 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.961 |
frr | rpsB | HLPCO_000121 | HLPCO_000118 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.979 |
frr | tsf | HLPCO_000121 | HLPCO_000119 | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Elongation factor T protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.990 |
pyrH | frr | HLPCO_000120 | HLPCO_000121 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.998 |
pyrH | rplA | HLPCO_000120 | HLPCO_001385 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.730 |
pyrH | rplK | HLPCO_000120 | HLPCO_001386 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.604 |
pyrH | rplM | HLPCO_000120 | HLPCO_001300 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.468 |
pyrH | rplO | HLPCO_000120 | HLPCO_001355 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.504 |
pyrH | rplP | HLPCO_000120 | HLPCO_001367 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.450 |
pyrH | rpsB | HLPCO_000120 | HLPCO_000118 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.959 |
pyrH | tsf | HLPCO_000120 | HLPCO_000119 | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | Elongation factor T protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.987 |
rplA | frr | HLPCO_001385 | HLPCO_000121 | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Ribosome-recycling factor protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.963 |
rplA | pyrH | HLPCO_001385 | HLPCO_000120 | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | Uridylate kinase protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.730 |