node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
all0771 | alr4853 | gene:10492782 | gene:10496907 | 4-hydroxyphenylpyruvate dioxygenase; ORF_ID:all0771. | Aspartate aminotransferase; ORF_ID:alr4853. | 0.915 |
all0771 | hisC-3 | gene:10492782 | gene:10497021 | 4-hydroxyphenylpyruvate dioxygenase; ORF_ID:all0771. | Histidinol-phosphate aminotransferase; ORF_ID:all4966; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.917 |
all1141 | alr4334 | gene:10493155 | gene:10496383 | Prephenate dehydrogenase; ORF_ID:all1141. | Prephenate dehydratase; ORF_ID:alr4334. | 0.994 |
all1141 | alr4853 | gene:10493155 | gene:10496907 | Prephenate dehydrogenase; ORF_ID:all1141. | Aspartate aminotransferase; ORF_ID:alr4853. | 0.906 |
all1141 | hisC-3 | gene:10493155 | gene:10497021 | Prephenate dehydrogenase; ORF_ID:all1141. | Histidinol-phosphate aminotransferase; ORF_ID:all4966; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.966 |
all1368 | all3263 | gene:10493383 | gene:10495301 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | 0.999 |
all1368 | alr4334 | gene:10493383 | gene:10496383 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Prephenate dehydratase; ORF_ID:alr4334. | 0.450 |
all1368 | hisB-2 | gene:10493383 | gene:10496439 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Imidazoleglycerol-phosphate dehydratase; ORF_ID:all4390. | 0.997 |
all1368 | hisC-3 | gene:10493383 | gene:10497021 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Histidinol-phosphate aminotransferase; ORF_ID:all4966; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.917 |
all1368 | hisD | gene:10493383 | gene:10493607 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.960 |
all1368 | hisD-2 | gene:10493383 | gene:10495092 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.960 |
all1368 | hisF | gene:10493383 | gene:10494930 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | 0.999 |
all3263 | all1368 | gene:10495301 | gene:10493383 | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
all3263 | alr4334 | gene:10495301 | gene:10496383 | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | Prephenate dehydratase; ORF_ID:alr4334. | 0.431 |
all3263 | hisB-2 | gene:10495301 | gene:10496439 | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | Imidazoleglycerol-phosphate dehydratase; ORF_ID:all4390. | 0.999 |
all3263 | hisC-3 | gene:10495301 | gene:10497021 | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | Histidinol-phosphate aminotransferase; ORF_ID:all4966; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.996 |
all3263 | hisD | gene:10495301 | gene:10493607 | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
all3263 | hisD-2 | gene:10495301 | gene:10495092 | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
all3263 | hisF | gene:10495301 | gene:10494930 | Histidine biosynthesis bifunctional protein; ORF_ID:all3263; In the C-terminal section; belongs to the PRA-PH family. | Imidazoleglycerol-phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | 0.999 |
alr4334 | all1141 | gene:10496383 | gene:10493155 | Prephenate dehydratase; ORF_ID:alr4334. | Prephenate dehydrogenase; ORF_ID:all1141. | 0.994 |