node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAG_00786 | EAG_06147 | E2AN89 | E2A3B3 | Crossover junction endonuclease MUS81. | DNA repair endonuclease XPF. | 0.929 |
EAG_00786 | EAG_06609 | E2AN89 | E2A770 | Crossover junction endonuclease MUS81. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.726 |
EAG_00786 | EAG_07249 | E2AN89 | E2AMP2 | Crossover junction endonuclease MUS81. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.847 |
EAG_00786 | EAG_09446 | E2AN89 | E1ZV67 | Crossover junction endonuclease MUS81. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. | 0.571 |
EAG_00786 | EAG_11441 | E2AN89 | E2A9M1 | Crossover junction endonuclease MUS81. | Uncharacterized protein. | 0.561 |
EAG_00786 | EAG_14711 | E2AN89 | E2A945 | Crossover junction endonuclease MUS81. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.604 |
EAG_00786 | EAG_16386 | E2AN89 | E2AV90 | Crossover junction endonuclease MUS81. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.726 |
EAG_03728 | EAG_06609 | E2A195 | E2A770 | Coiled-coil domain-containing protein 111. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.869 |
EAG_03728 | EAG_09446 | E2A195 | E1ZV67 | Coiled-coil domain-containing protein 111. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. | 0.913 |
EAG_03728 | EAG_11441 | E2A195 | E2A9M1 | Coiled-coil domain-containing protein 111. | Uncharacterized protein. | 0.962 |
EAG_03728 | EAG_16386 | E2A195 | E2AV90 | Coiled-coil domain-containing protein 111. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.869 |
EAG_06147 | EAG_00786 | E2A3B3 | E2AN89 | DNA repair endonuclease XPF. | Crossover junction endonuclease MUS81. | 0.929 |
EAG_06147 | EAG_06609 | E2A3B3 | E2A770 | DNA repair endonuclease XPF. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.860 |
EAG_06147 | EAG_07249 | E2A3B3 | E2AMP2 | DNA repair endonuclease XPF. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.788 |
EAG_06147 | EAG_09446 | E2A3B3 | E1ZV67 | DNA repair endonuclease XPF. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. | 0.585 |
EAG_06147 | EAG_11441 | E2A3B3 | E2A9M1 | DNA repair endonuclease XPF. | Uncharacterized protein. | 0.642 |
EAG_06147 | EAG_14711 | E2A3B3 | E2A945 | DNA repair endonuclease XPF. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.785 |
EAG_06147 | EAG_16386 | E2A3B3 | E2AV90 | DNA repair endonuclease XPF. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.860 |
EAG_06609 | EAG_00786 | E2A770 | E2AN89 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Crossover junction endonuclease MUS81. | 0.726 |
EAG_06609 | EAG_03728 | E2A770 | E2A195 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Coiled-coil domain-containing protein 111. | 0.869 |