node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAG_02967 | EAG_06609 | E2AUC9 | E2A770 | CDC45-related protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.709 |
EAG_02967 | EAG_06852 | E2AUC9 | E2A1J5 | CDC45-related protein. | WD repeat and HMG-box DNA-binding protein 1. | 0.997 |
EAG_02967 | EAG_08681 | E2AUC9 | E1ZVI3 | CDC45-related protein. | DNA replication complex GINS protein PSF3. | 0.996 |
EAG_02967 | EAG_09208 | E2AUC9 | E2AKY8 | CDC45-related protein. | Claspin. | 0.951 |
EAG_02967 | EAG_11441 | E2AUC9 | E2A9M1 | CDC45-related protein. | Uncharacterized protein. | 0.764 |
EAG_02967 | EAG_11482 | E2AUC9 | E2A9R2 | CDC45-related protein. | Serine/threonine-protein kinase grp; Belongs to the protein kinase superfamily. | 0.964 |
EAG_02967 | EAG_12788 | E2AUC9 | E2A5U9 | CDC45-related protein. | Protein MCM10-like protein. | 0.998 |
EAG_02967 | EAG_15328 | E2AUC9 | E2AHY1 | CDC45-related protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Belongs to the MCM family. | 0.999 |
EAG_02967 | EAG_16386 | E2AUC9 | E2AV90 | CDC45-related protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.709 |
EAG_03728 | EAG_06609 | E2A195 | E2A770 | Coiled-coil domain-containing protein 111. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.869 |
EAG_03728 | EAG_09208 | E2A195 | E2AKY8 | Coiled-coil domain-containing protein 111. | Claspin. | 0.969 |
EAG_03728 | EAG_11441 | E2A195 | E2A9M1 | Coiled-coil domain-containing protein 111. | Uncharacterized protein. | 0.962 |
EAG_03728 | EAG_16386 | E2A195 | E2AV90 | Coiled-coil domain-containing protein 111. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.869 |
EAG_06609 | EAG_02967 | E2A770 | E2AUC9 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | CDC45-related protein. | 0.709 |
EAG_06609 | EAG_03728 | E2A770 | E2A195 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Coiled-coil domain-containing protein 111. | 0.869 |
EAG_06609 | EAG_06852 | E2A770 | E2A1J5 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | WD repeat and HMG-box DNA-binding protein 1. | 0.402 |
EAG_06609 | EAG_09208 | E2A770 | E2AKY8 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Claspin. | 0.889 |
EAG_06609 | EAG_11441 | E2A770 | E2A9M1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Uncharacterized protein. | 0.966 |
EAG_06609 | EAG_11482 | E2A770 | E2A9R2 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Serine/threonine-protein kinase grp; Belongs to the protein kinase superfamily. | 0.606 |
EAG_06609 | EAG_12788 | E2A770 | E2A5U9 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Protein MCM10-like protein. | 0.607 |