STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSC_14565Meta cleavage compound hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (274 aa)    
Predicted Functional Partners:
DSC_14570
Protocatechuate 4,5-dioxygenase subunit beta.
 
 
 0.963
DSC_14575
Subunit of meta cleavage enzyme.
    
  0.951
DSC_09160
COG3971 2-keto-4-pentenoate hydratase.
 
 
 0.934
DSC_09165
4-oxalocrotonate decarboxylase; COG3971 2-keto-4-pentenoate hydratase.
 
 
 0.934
DSC_09365
2-hydroxypenta-2,4-dienoate hydratase (BphH); COG3971 2-keto-4-pentenoate hydratase.
 
 
 0.933
bphD
2-hydroxy-6-oxo-6-phenylhexa-2,4- dienoate hydrolase (BphD); Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo- 6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic acid and 2- hydroxy-2,4-pentadienoic acid (HPD); Belongs to the AB hydrolase superfamily. BphD family.
  
  
 
0.922
DSC_14580
Terminal oxygenase component of carbazole 1,9a-dioxygenase; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.
 
 
   0.729
DSC_09355
2,3-dihydroxybiphenyl-1,2-dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.
  
 
  0.674
DSC_09370
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.528
DSC_09375
4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
  
 0.521
Your Current Organism:
Pseudoxanthomonas spadix
NCBI taxonomy Id: 1045855
Other names: P. spadix BD-a59, Pseudoxanthomonas spadix BD-a59, Pseudoxanthomonas spadix str. BD-a59, Pseudoxanthomonas spadix strain BD-a59
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