node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DSC_00995 | DSC_02155 | DSC_00995 | DSC_02155 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | 0.506 |
DSC_00995 | DSC_07730 | DSC_00995 | DSC_07730 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase. | 0.933 |
DSC_00995 | DSC_11610 | DSC_00995 | DSC_11610 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. | 0.999 |
DSC_00995 | DSC_13050 | DSC_00995 | DSC_13050 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease IX; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | 0.974 |
DSC_00995 | DSC_15135 | DSC_00995 | DSC_15135 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA ligase; COG1793 ATP-dependent DNA ligase. | 0.933 |
DSC_00995 | ligA | DSC_00995 | DSC_07880 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.432 |
DSC_00995 | polA | DSC_00995 | DSC_00480 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
DSC_02155 | DSC_00995 | DSC_02155 | DSC_00995 | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.506 |
DSC_02155 | DSC_07730 | DSC_02155 | DSC_07730 | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | ATP-dependent DNA ligase. | 0.474 |
DSC_02155 | DSC_11610 | DSC_02155 | DSC_11610 | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. | 0.406 |
DSC_02155 | DSC_13050 | DSC_02155 | DSC_13050 | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | Exodeoxyribonuclease IX; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | 0.890 |
DSC_02155 | DSC_15135 | DSC_02155 | DSC_15135 | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | DNA ligase; COG1793 ATP-dependent DNA ligase. | 0.474 |
DSC_02155 | polA | DSC_02155 | DSC_00480 | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.920 |
DSC_07730 | DSC_00995 | DSC_07730 | DSC_00995 | ATP-dependent DNA ligase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.933 |
DSC_07730 | DSC_02155 | DSC_07730 | DSC_02155 | ATP-dependent DNA ligase. | Hypothetical protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family. | 0.474 |
DSC_07730 | DSC_11570 | DSC_07730 | DSC_11570 | ATP-dependent DNA ligase. | COG0681 Signal peptidase I; Belongs to the peptidase S26 family. | 0.510 |
DSC_07730 | DSC_11610 | DSC_07730 | DSC_11610 | ATP-dependent DNA ligase. | DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. | 0.660 |
DSC_07730 | DSC_13050 | DSC_07730 | DSC_13050 | ATP-dependent DNA ligase. | Exodeoxyribonuclease IX; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | 0.519 |
DSC_07730 | DSC_15135 | DSC_07730 | DSC_15135 | ATP-dependent DNA ligase. | DNA ligase; COG1793 ATP-dependent DNA ligase. | 0.900 |
DSC_07730 | hisB | DSC_07730 | DSC_09930 | ATP-dependent DNA ligase. | Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0241 Histidinol phosphatase and related phosphatases; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.582 |