STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (906 aa)    
Predicted Functional Partners:
mqo
Malate/quinone oxidoreductase.
    
 0.936
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
  
  
 0.934
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.930
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.926
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.926
gltB
Glutamate synthase (ferredoxin).
  
  
 0.852
aceB
Malate synthase A; Belongs to the malate synthase family.
     
 0.852
gltA-2
2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
  
 0.847
gltA
Citrate (Si)-synthase; Belongs to the citrate synthase family.
     
 0.826
hoxU
Formate dehydrogenase, alpha subunit.
     
 0.801
Your Current Organism:
Alicyclobacillus acidocaldarius Tc41
NCBI taxonomy Id: 1048834
Other names: A. acidocaldarius subsp. acidocaldarius Tc-4-1, Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1, Alicyclobacillus acidocaldarius subsp. acidocaldarius str. Tc-4-1, Alicyclobacillus acidocaldarius subsp. acidocaldarius strain Tc-4-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.