STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (473 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.998
ABD09873.1
uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase.
 
  
 0.992
ABD09874.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.991
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 0.988
ABD13129.1
Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.987
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.972
ABD09912.1
uroporphyrinogen-III C-methyltransferase.
 
  
 0.879
ABD10180.1
uroporphyrinogen-III C-methyltransferase.
 
  
 0.878
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.876
rex
CoA-binding; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.824
Your Current Organism:
Frankia casuarinae
NCBI taxonomy Id: 106370
Other names: CECT 9043, DSM 45818, F. casuarinae, Frankia casuarinae Nouioui et al. 2016, Frankia sp. BR, Frankia sp. CcI3, Frankia sp. Cg70.9, Frankia sp. Thr, strain CcI3
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.