STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNEG_023553-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1584 aa)    
Predicted Functional Partners:
PNEG_01430
Chorismate synthase.
 
 
 0.987
PNEG_02399
Uncharacterized protein.
    
 0.952
PNEG_03111
Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family.
   
 0.944
PNEG_02726
Carbamoyl-phosphate synthase, large subunit.
  
 
 0.943
PNEG_02507
Aminodeoxychorismate synthase.
  
 
 0.940
PNEG_02648
Uncharacterized protein; Belongs to the adenylate kinase family.
    
 0.894
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
    
 0.894
PNEG_00209
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
    
 0.891
PNEG_02473
Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.
  
  
 0.853
PNEG_01304
Uncharacterized protein.
   
 0.842
Your Current Organism:
Pneumocystis murina
NCBI taxonomy Id: 1069680
Other names: P. murina B123, Pneumocystis murina B123
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