node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCD29466.1 | cysS | CAGGBEG34_240037 | CAGGBEG34_240036 | Putative DNA-3-methyladenine glycosylase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme. | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.797 |
CCD29466.1 | rplQ | CAGGBEG34_240037 | CAGGBEG34_240035 | Putative DNA-3-methyladenine glycosylase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme. | 50S ribosomal subunit protein L17; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type s:structure. | 0.773 |
CCD29466.1 | rpoA | CAGGBEG34_240037 | CAGGBEG34_240034 | Putative DNA-3-methyladenine glycosylase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.681 |
CCD29466.1 | rpsD | CAGGBEG34_240037 | CAGGBEG34_240033 | Putative DNA-3-methyladenine glycosylase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme. | 30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.642 |
cysS | CCD29466.1 | CAGGBEG34_240036 | CAGGBEG34_240037 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Putative DNA-3-methyladenine glycosylase; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe:putative enzyme. | 0.797 |
cysS | glyA | CAGGBEG34_240036 | CAGGBEG34_280052 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.763 |
cysS | guaA | CAGGBEG34_240036 | CAGGBEG34_180086 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | 0.711 |
cysS | metG | CAGGBEG34_240036 | CAGGBEG34_250041 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.739 |
cysS | pheT | CAGGBEG34_240036 | CAGGBEG34_200026 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.737 |
cysS | rplQ | CAGGBEG34_240036 | CAGGBEG34_240035 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 50S ribosomal subunit protein L17; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type s:structure. | 0.794 |
cysS | rpoA | CAGGBEG34_240036 | CAGGBEG34_240034 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.753 |
cysS | rpsD | CAGGBEG34_240036 | CAGGBEG34_240033 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.722 |
cysS | tpiA | CAGGBEG34_240036 | CAGGBEG34_180112 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Triosephosphate isomerase (TIM) (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.822 |
cysS | trmJ | CAGGBEG34_240036 | CAGGBEG34_450003 | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | Putative tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.747 |
glyA | cysS | CAGGBEG34_280052 | CAGGBEG34_240036 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.763 |
glyA | guaA | CAGGBEG34_280052 | CAGGBEG34_180086 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | 0.893 |
glyA | metG | CAGGBEG34_280052 | CAGGBEG34_250041 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.705 |
glyA | pheT | CAGGBEG34_280052 | CAGGBEG34_200026 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.611 |
glyA | tpiA | CAGGBEG34_280052 | CAGGBEG34_180112 | Serine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Triosephosphate isomerase (TIM) (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.479 |
guaA | cysS | CAGGBEG34_180086 | CAGGBEG34_240036 | GMP synthase (glutamine-hydrolyzing) (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type e:enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.711 |