STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucA2-oxoglutarate dehydrogenase, E1 component; Annotation based on TIGRFAM 2oxo_dh_E1 protein motif and similarity to AA sequences in nr. (908 aa)    
Predicted Functional Partners:
sucB
2-oxoglutarate dehydrogenase, E2 component; Annotation based on TIGRFAM SucB_Actino protein motif and similarity to AA sequences in nr.
 
 0.999
sucB-2
2-oxoglutarate dehydrogenase, E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
lpd
Dihydrolipoamide dehydrogenase; Annotation based on TIGRFAM lipoamide_DH protein motif and similarity to AA sequences in nr.
  
 0.993
lpdA
Dihydrolipoamide dehydrogenase; Annotation based on TIGRFAM lipoamide_DH protein motif and similarity to AA sequences in nr.
  
 0.993
icd
Isocitrate dehydrogenase (NADP+); Annotation based on TIGRFAM nadp_idh_euk protein motif and similarity to AA sequences in nr; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 
 0.963
aceF
Dihydrolipoamide acyltransferase E2 component; Annotation based on TIGRFAM PDHac_trf_mito protein motif and similarity to AA sequences in nr.
 
 0.961
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.932
sucD
succinyl-CoA ligase (ADP-forming) subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.903
sdhA
Succinate dehydrogenase flavoprotein subunit; Annotation based on TIGRFAM sdhA_Bsu protein motif and similarity to AA sequences in nr.
  
 
 0.896
sucA-2
2-oxoglutarate dehydrogenase E1 component; Annotation based on TIGRFAM 2oxo_dh_E1 protein motif and similarity to AA sequences in nr.
   
 0.885
Your Current Organism:
Blattabacterium sp. MADAR
NCBI taxonomy Id: 1074889
Other names: B. sp. (Mastotermes darwiniensis) str. MADAR, Blattabacterium sp. (Mastotermes darwiniensis) str. MADAR, Blattabacterium sp. (Mastotermes darwiniensis) strain MADAR
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