STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkCADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (495 aa)    
Predicted Functional Partners:
ETA68643.1
Archaeal ADP-dependent phosphofructokinase/glucokinase; IMG reference gene:2515107472; PFAM: ADP-specific Phosphofructokinase/Glucokinase conserved region.
 
  
0.962
ETA68589.1
DhnA-type fructose-1,6-bisphosphate aldolase-like enzyme; IMG reference gene:2515107417; PFAM: DeoC/LacD family aldolase.
 
  
 0.847
ETA68604.1
Fructose-1,6-bisphosphatase, class II; IMG reference gene:2515107432; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II; Belongs to the FBPase class 2 family.
  
  
 0.832
ETA68744.1
Putative glycerate kinase; IMG reference gene:2515107578; PFAM: MOFRL family; Domain of unknown function (DUF4147).
  
  
 0.821
ETA67617.1
Thermophilic glucose-6-phosphate isomerase-like enzyme; IMG reference gene:2515106399; PFAM: Glucose-6-phosphate isomerase (GPI).
    
 0.820
ETA68644.1
IMG reference gene:2515107473; PFAM: HhH-GPD superfamily base excision DNA repair protein; 8-oxoguanine DNA glycosylase, N-terminal domain; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg).
       0.807
ETA67696.1
Phosphoglucosamine mutase; IMG reference gene:2515106482; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase; Belongs to the phosphohexose mutase family.
    
 0.796
aroA
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.796
aroA-2
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.796
ETA67461.1
Dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like; IMG reference gene:2515106240; PFAM: Enoyl-(Acyl carrier protein) reductase.
     
 0.734
Your Current Organism:
Methanolobus tindarius
NCBI taxonomy Id: 1090322
Other names: M. tindarius DSM 2278, Methanolobus tindarius DSM 2278, Methanolobus tindarius str. DSM 2278, Methanolobus tindarius strain DSM 2278
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.