SPATA5 protein (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPATA5

Spermatogenesis associated 5. (887 aa)

Predicted Functional Partners:

ubxn7

0.999

ufd1

0.960

derl1

0.955

nsfl1c

0.953

derl2

0.951

yod1

0.948

ubxn1

0.936

LOC109509695

0.916

ENSHCOP00000015413

0.902

psmb2

0.897

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000015413	SPATA5	ENSHCOP00000015413	ENSHCOP00000019051	Ataxin 3.	Spermatogenesis associated 5.	0.902
ENSHCOP00000015413	ufd1	ENSHCOP00000015413	ENSHCOP00000004322	Ataxin 3.	Ubiquitin recognition factor in ER associated degradation 1.	0.594
LOC109509695	SPATA5	ENSHCOP00000015189	ENSHCOP00000019051	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	Spermatogenesis associated 5.	0.916
LOC109509695	derl1	ENSHCOP00000015189	ENSHCOP00000007921	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.998
LOC109509695	derl2	ENSHCOP00000015189	ENSHCOP00000010890	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.999
LOC109509695	ufd1	ENSHCOP00000015189	ENSHCOP00000004322	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	Ubiquitin recognition factor in ER associated degradation 1.	0.631
SPATA5	ENSHCOP00000015413	ENSHCOP00000019051	ENSHCOP00000015413	Spermatogenesis associated 5.	Ataxin 3.	0.902
SPATA5	LOC109509695	ENSHCOP00000019051	ENSHCOP00000015189	Spermatogenesis associated 5.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.916
SPATA5	derl1	ENSHCOP00000019051	ENSHCOP00000007921	Spermatogenesis associated 5.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.955
SPATA5	derl2	ENSHCOP00000019051	ENSHCOP00000010890	Spermatogenesis associated 5.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.951
SPATA5	nsfl1c	ENSHCOP00000019051	ENSHCOP00000005865	Spermatogenesis associated 5.	NSFL1 (p97) cofactor (p47).	0.953
SPATA5	psmb2	ENSHCOP00000019051	ENSHCOP00000002607	Spermatogenesis associated 5.	Proteasome subunit beta.	0.897
SPATA5	ubxn1	ENSHCOP00000019051	ENSHCOP00000020608	Spermatogenesis associated 5.	UBX domain protein 1.	0.936
SPATA5	ubxn7	ENSHCOP00000019051	ENSHCOP00000010781	Spermatogenesis associated 5.	UBX domain protein 7.	0.999
SPATA5	ufd1	ENSHCOP00000019051	ENSHCOP00000004322	Spermatogenesis associated 5.	Ubiquitin recognition factor in ER associated degradation 1.	0.960
SPATA5	yod1	ENSHCOP00000019051	ENSHCOP00000017765	Spermatogenesis associated 5.	YOD1 deubiquitinase.	0.948
derl1	LOC109509695	ENSHCOP00000007921	ENSHCOP00000015189	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.998
derl1	SPATA5	ENSHCOP00000007921	ENSHCOP00000019051	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Spermatogenesis associated 5.	0.955
derl1	derl2	ENSHCOP00000007921	ENSHCOP00000010890	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.997
derl1	nsfl1c	ENSHCOP00000007921	ENSHCOP00000005865	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NSFL1 (p97) cofactor (p47).	0.954