node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
E0L32_000731 | E0L32_001447 | A0A507B1G4 | A0A507B125 | Uncharacterized protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.788 |
E0L32_000731 | E0L32_010081 | A0A507B1G4 | A0A507APP4 | Uncharacterized protein. | NADPH:adrenodoxin oxidoreductase, mitochondrial. | 0.903 |
E0L32_000731 | E0L32_012378 | A0A507B1G4 | A0A507BJD9 | Uncharacterized protein. | Amidohydro-rel domain-containing protein. | 0.446 |
E0L32_000731 | NCS6 | A0A507B1G4 | A0A507BH96 | Uncharacterized protein. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.695 |
E0L32_001447 | E0L32_000731 | A0A507B125 | A0A507B1G4 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uncharacterized protein. | 0.788 |
E0L32_001447 | E0L32_003240 | A0A507B125 | A0A507B4D6 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uncharacterized protein. | 0.850 |
E0L32_001447 | E0L32_010081 | A0A507B125 | A0A507APP4 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | NADPH:adrenodoxin oxidoreductase, mitochondrial. | 0.779 |
E0L32_001447 | E0L32_010156 | A0A507B125 | A0A507AP16 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Pribosyltran domain-containing protein. | 0.972 |
E0L32_001447 | E0L32_012116 | A0A507B125 | A0A507B5R0 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. | 0.916 |
E0L32_001447 | E0L32_012378 | A0A507B125 | A0A507BJD9 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Amidohydro-rel domain-containing protein. | 0.642 |
E0L32_001447 | NCS6 | A0A507B125 | A0A507BH96 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.799 |
E0L32_003240 | E0L32_001447 | A0A507B4D6 | A0A507B125 | Uncharacterized protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.850 |
E0L32_003240 | E0L32_010156 | A0A507B4D6 | A0A507AP16 | Uncharacterized protein. | Pribosyltran domain-containing protein. | 0.721 |
E0L32_003240 | E0L32_012378 | A0A507B4D6 | A0A507BJD9 | Uncharacterized protein. | Amidohydro-rel domain-containing protein. | 0.617 |
E0L32_004227 | E0L32_012378 | A0A507BDU5 | A0A507BJD9 | Nudix hydrolase domain-containing protein. | Amidohydro-rel domain-containing protein. | 0.428 |
E0L32_010081 | E0L32_000731 | A0A507APP4 | A0A507B1G4 | NADPH:adrenodoxin oxidoreductase, mitochondrial. | Uncharacterized protein. | 0.903 |
E0L32_010081 | E0L32_001447 | A0A507APP4 | A0A507B125 | NADPH:adrenodoxin oxidoreductase, mitochondrial. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.779 |
E0L32_010081 | E0L32_012378 | A0A507APP4 | A0A507BJD9 | NADPH:adrenodoxin oxidoreductase, mitochondrial. | Amidohydro-rel domain-containing protein. | 0.458 |
E0L32_010081 | NCS6 | A0A507APP4 | A0A507BH96 | NADPH:adrenodoxin oxidoreductase, mitochondrial. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.796 |
E0L32_010156 | E0L32_001447 | A0A507AP16 | A0A507B125 | Pribosyltran domain-containing protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.972 |