STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kex1Pheromone-processing carboxypeptidase kex1; Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity). (607 aa)    
Predicted Functional Partners:
Pc12g05830
Pc12g05830 protein.
      
 0.709
Pc22g18210
Pc22g18210 protein; Belongs to the peptidase A1 family.
   
 0.687
Pc22g02910
Pc22g02910 protein; Belongs to the peptidase S8 family.
   
 
 0.644
Pc22g00770
Pc22g00770 protein.
      
 0.630
Pc15g01800
Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
    
 
 0.622
dapB
Probable dipeptidyl-aminopeptidase B; Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N- termini provided that the penultimate residue is proline.
      
 0.599
Pc14g00080
Pc14g00080 protein.
      
 0.590
atg8
Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved [...]
   
  
 0.568
Pc21g14560
Glyceraldehyde-3-phosphate dehydrogenase.
      
 0.566
Pc20g12060
E3 ubiquitin protein ligase.
      
 0.463
Your Current Organism:
Penicillium rubens
NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255
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