STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pc18g05890Pc18g05890 protein. (359 aa)    
Predicted Functional Partners:
Pc16g06870
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
 0.986
Pc12g11860
Pc12g11860 protein.
  
 
 0.926
Pc14g01170
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
0.849
Lys7
Saccharopine reductase Lys7-Penicillium chrysogenum.
   
  
 0.843
lys1
Homocitrate synthase, mitochondrial; Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
  
 0.755
Pc22g18410
Pc22g18410 protein.
  
 
 0.693
trpC
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
  
 0.684
Pc18g05450
Pc18g05450 protein.
  
 0.669
Pc18g01240
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.
   
  
 0.658
Pc20g01920
Pc20g01920 protein.
 
 0.656
Your Current Organism:
Penicillium rubens
NCBI taxonomy Id: 500485
Other names: P. rubens Wisconsin 54-1255, Penicillium rubens Wisconsin 54-1255
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.