STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFOrotidine 5`-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.998
pyrB
Probable aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.970
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
 
  
 0.963
CCE98071.1
Putative benzoate 1,2-dioxygenase electron transfer component.
  
  
 0.960
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
  
  
 0.948
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.942
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.939
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.920
CCE97351.1
Putative 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
  0.901
mazG
Protein mazG homolog.
     
  0.900
Your Current Organism:
Sinorhizobium fredii HH103
NCBI taxonomy Id: 1117943
Other names: S. fredii HH103, Sinorhizobium fredii str. HH103, Sinorhizobium fredii strain HH103
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.