STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsrBDissimilatory Sulfite Reductase I, chain B; Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria. (386 aa)    
Predicted Functional Partners:
dsrA
Dissimilatory Sulfite Reductase I, chain A; Part of the complex that catalyzes the reduction of sulfite to sulfide. The alpha and beta subunits may have arisen by gene duplication. They both bind 2 iron-sulfur clusters, but the alpha subunit seems to be catalytically inactive, due to substitutions along the putative substrate access channel, and because it binds sirohydrochlorin (the dematallated form of siroheme) instead of siroheme.
 
0.999
dsrC
Putative dissimilatory sulfite reductase, gamma subunit.
 
 
 
 0.998
aprB
Adenylylsulfate Reductase; Iron-sulfur cluster subunit of the adenylylsulfate reductase which catalyzes reversibly the reduction of adenosine 5'-phosphosulfate (APS) to sulfite and AMP during dissimilatory sulfate reduction. The iron-sulfur cluster 2 is thought to accept electrons from a still unknown electron donor and transfer electrons to the iron-sulfur cluster 1 of this protein and then onto the FAD of AprA.
 
 
 0.985
aprA
Adenylylsulfate Reductase; Catalytic subunit of the adenylylsulfate reductase which catalyzes reversibly the reduction of adenosine 5'-phosphosulfate (APS) to sulfite and AMP during dissimilatory sulfate reduction. Belongs to the FAD-dependent oxidoreductase 2 family.
 
 
 0.984
dsrD
Putative dissimilatory sulfite reductase B.
 
 
 
 0.967
paps
Putative phosphoadenosine phosphosulfate reductase.
    
 0.916
floxA
Putative Dihydroorotate dehydrogenase, electron transfer subunit protein.
    
 0.911
DGI_0241
Putative Nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
    
 0.910
cysK
Putative cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.910
DGI_2741
Putative 4Fe-4S ferredoxin iron-sulfur binding domain protein.
    
 0.909
Your Current Organism:
Desulfovibrio gigas
NCBI taxonomy Id: 1121448
Other names: D. gigas DSM 1382 = ATCC 19364, Desulfovibrio gigas ATCC 19364, Desulfovibrio gigas DSM 1382 = ATCC 19364
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