STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (382 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase.
 
 0.999
hisI
phosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family.
 
  
 0.999
SHJ26435.1
Aspartate aminotransferase.
  
 
0.985
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
 0.985
SHK16011.1
Prephenate dehydrogenase.
  
 
 0.979
SHJ25499.1
Chorismate mutase / prephenate dehydratase.
  
 
 0.962
hisF
Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
 
 0.931
hisH
Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
 
 0.920
SHJ98344.1
Histidinol-phosphatase (PHP family); Belongs to the PHP hydrolase family. HisK subfamily.
 
 
 0.914
SHK72262.1
Histidinol-phosphatase (PHP family); Belongs to the PHP hydrolase family. HisK subfamily.
  
 
 0.901
Your Current Organism:
Hespellia stercorisuis
NCBI taxonomy Id: 1121950
Other names: H. stercorisuis DSM 15480, Hespellia stercorisuis DSM 15480
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