STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDW13715.1Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (912 aa)    
Predicted Functional Partners:
SDW69590.1
Isocitrate dehydrogenase (NADP).
 
 0.933
SDW69621.1
Citrate synthase; Belongs to the citrate synthase family.
 
 0.920
SDW59183.1
Citrate synthase; Belongs to the citrate synthase family.
 
 0.919
SDW84326.1
Citrate synthase; Belongs to the citrate synthase family.
 
 0.910
SDW08394.1
3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.807
SDW59233.1
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
 0.786
SDW24405.1
Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.752
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.720
rpmB
LSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family.
   
   0.701
SDW59208.1
2-methylcitrate dehydratase.
  
 
 0.701
Your Current Organism:
Marinococcus luteus
NCBI taxonomy Id: 1122204
Other names: CCTCC AA 208014, DSM 23126, KCTC 13214, M. luteus, Marinococcus luteus Wang et al. 2009, YIM 91094
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