STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK51057.1Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa)    
Predicted Functional Partners:
SHK50989.1
Serine O-acetyltransferase.
 
 0.996
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.958
SHJ93031.1
CoA-disulfide reductase; Belongs to the sulfur carrier protein TusA family.
  
 
 0.947
SHJ69312.1
Cystathionine gamma-lyase.
 0.933
SHJ84108.1
Methionine-gamma-lyase.
 
 0.921
SHJ58048.1
Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
    
  0.848
luxS
S-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.845
SHJ69072.1
Anaerobic sulfite reductase subunit C; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
  0.844
SHJ80599.1
Aspartate aminotransferase.
     
 0.842
SHJ69117.1
Anaerobic sulfite reductase subunit B.
   
 
  0.841
Your Current Organism:
Tepidibacter formicigenes
NCBI taxonomy Id: 1123349
Other names: T. formicigenes DSM 15518, Tepidibacter formicigenes DSM 15518
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