node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCF64269.1 | gmk | NOCYR_3505 | NOCYR_3504 | Integration host factor; Function of strongly homologous gene; regulator. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.913 |
CCF64269.1 | guaA | NOCYR_3505 | NOCYR_0951 | Integration host factor; Function of strongly homologous gene; regulator. | GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | 0.637 |
CCF64269.1 | ndk | NOCYR_3505 | NOCYR_1414 | Integration host factor; Function of strongly homologous gene; regulator. | Nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.464 |
CCF64269.1 | pykA | NOCYR_3505 | NOCYR_2025 | Integration host factor; Function of strongly homologous gene; regulator. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.811 |
CCF64269.1 | relA | NOCYR_3505 | NOCYR_3574 | Integration host factor; Function of strongly homologous gene; regulator. | GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.617 |
CCF64269.1 | rpoZ | NOCYR_3505 | NOCYR_3503 | Integration host factor; Function of strongly homologous gene; regulator. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.956 |
apt | gmk | NOCYR_3579 | NOCYR_3504 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.976 |
apt | guaA | NOCYR_3579 | NOCYR_0951 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | 0.996 |
apt | hpt | NOCYR_3579 | NOCYR_0397 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.968 |
apt | relA | NOCYR_3579 | NOCYR_3574 | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.464 |
gmk | CCF64269.1 | NOCYR_3504 | NOCYR_3505 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Integration host factor; Function of strongly homologous gene; regulator. | 0.913 |
gmk | apt | NOCYR_3504 | NOCYR_3579 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.976 |
gmk | guaA | NOCYR_3504 | NOCYR_0951 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP. | 0.984 |
gmk | hpt | NOCYR_3504 | NOCYR_0397 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine-guanine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.965 |
gmk | ndk | NOCYR_3504 | NOCYR_1414 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.936 |
gmk | nrdE | NOCYR_3504 | NOCYR_4072 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.915 |
gmk | nrdF | NOCYR_3504 | NOCYR_4067 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.909 |
gmk | pykA | NOCYR_3504 | NOCYR_2025 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.939 |
gmk | relA | NOCYR_3504 | NOCYR_3574 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.920 |
gmk | rpoZ | NOCYR_3504 | NOCYR_3503 | Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.984 |