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tuf protein (Nocardia cyriacigeorgica) - STRING interaction network
"tuf" - Elongation factor Tu in Nocardia cyriacigeorgica
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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tufElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (396 aa)    
Predicted Functional Partners:
rpsE
30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (215 aa)
 
  0.992
rpsG
30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (156 aa)
 
  0.992
rpsL
30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (124 aa)
 
  0.992
tsf
Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (274 aa)
   
  0.990
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes (101 aa)
 
  0.990
NOCYR_4860
Protein chain elongation factor EF-G, GTP-binding; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (700 aa)
 
0.988
NOCYR_1749
Elongation factor G-like protein (720 aa)
 
  0.987
rpsM
30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P- sites (123 aa)
 
 
  0.985
rpsK
30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (137 aa)
 
  0.985
rpsB
30S ribosomal protein S2 (277 aa)
 
  0.984
Your Current Organism:
Nocardia cyriacigeorgica
NCBI taxonomy Id: 1127134
Other names: N. cyriacigeorgica, N. cyriacigeorgica GUH-2, Nocardia cyriacigeorgica, Nocardia cyriacigeorgica GUH-2, Nocardia cyriacigeorgica corrig. Yassin et al. 2001, Nocardia cyriacigeorgica str. GUH-2, Nocardia cyriacigeorgica strain GUH-2, Nocardia cyriacigeorgici, Nocardia cyriacigeorgici (sic) Yassin et al. 2001
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