STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
valLValidoxylamine synthase; Involved in the biosynthesis of the antifungal agent validamycin A. Catalyzes the condensation between GDP-valienol and validamine 7-phosphate via a nonglycosidic C-N bond formation to yield validoxylamine A 7'-phosphate. Belongs to the glycosyltransferase 20 family. (497 aa)    
Predicted Functional Partners:
SHJG_0273
Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.979
SHJG_4828
Trehalose-6-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 
 0.979
valB
Nucleotidylyltransferase; Involved in the biosynthesis of the antifungal agent validamycin A. Catalyzes the conversion of valienol 1-phosphate to GDP-valienol. Also able to use efficiently ATP as nucleotidyl donor, but other NDP derivatives are less efficient ; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 0.933
SHJG_0271
Phosphatase/phosphohexomutase.
    
 0.907
SHJG_0272
Cyclitolreductase.
 
  
 0.853
SHJG_4896
Hypothetical protein.
  
  
 0.706
SHJG_0275
Dehydrogenase.
     
 0.588
SHJG_8199
Glycosyl hydrolase.
 
   
 0.585
SHJG_2469
Glycosyl hydrolase.
 
   
 0.577
SHJG_0284
Glycosyl hydrolase.
 
   
 0.545
Your Current Organism:
Streptomyces hygroscopicus jinggangensis
NCBI taxonomy Id: 1133850
Other names: S. hygroscopicus subsp. jinggangensis 5008, Streptomyces hygroscopicus subsp. jinggangensis 5008, Streptomyces hygroscopicus subsp. jinggangensis str. 5008, Streptomyces hygroscopicus subsp. jinggangensis strain 5008
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.