STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABB56588.1Two component transcriptional regulator, winged helix family. (237 aa)    
Predicted Functional Partners:
ABB57387.1
Multi-sensor signal transduction histidine kinase.
 
 
 0.901
sphS
PAS/PAC sensor signal transduction histidine kinase; Member of the two-component regulatory system SphR/SphS. Sensory kinase. Is involved in inducible production of alkaline phosphatase in response to phosphate limitation as it is directly involved in the regulation of phoA transcription in response to phosphate limitation. SphS functions as a protein kinase that phosphorylates SphR.
 
   0.848
ABB56512.1
GAF sensor signal transduction histidine kinase.
 
 0.847
SEC0020
Periplasmic sensor signal transduction histidine kinase.
 
   0.836
ABB56485.1
GAF sensor signal transduction histidine kinase.
  
   0.831
sasA
Histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
 
   0.813
ABB57902.1
Histidine kinase.
 
   0.795
nblS
Multi-sensor signal transduction histidine kinase.
 
 
 0.767
cikA
GAF sensor hybrid histidine kinase.
 
   0.687
ABB58312.1
GAF sensor signal transduction histidine kinase.
 
   0.682
Your Current Organism:
Synechococcus elongatus
NCBI taxonomy Id: 1140
Other names: Anacystis nidulans R2, S. elongatus PCC 7942, Synechococcus elongatus PCC 7942, Synechococcus leopoliensis UTEX 2434, Synechococcus leopoliensis strain PCC 7942, Synechococcus sp. IAM M-200, Synechococcus sp. PCC 7942
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.