node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABB57296.1 | ABB57523.1 | Synpcc7942_1266 | Synpcc7942_1493 | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | MazG family protein. | 0.903 |
ABB57296.1 | ABB57861.1 | Synpcc7942_1266 | Synpcc7942_1831 | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMP dehydrogenase related 2. | 0.945 |
ABB57296.1 | guaA | Synpcc7942_1266 | Synpcc7942_0189 | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.973 |
ABB57296.1 | ndk | Synpcc7942_1266 | Synpcc7942_2497 | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.928 |
ABB57296.1 | surE | Synpcc7942_1266 | Synpcc7942_2063 | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Exopolyphosphatase / 5'-nucleotidase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
ABB57522.1 | ABB57523.1 | Synpcc7942_1492 | Synpcc7942_1493 | Conserved hypothetical protein. | MazG family protein. | 0.796 |
ABB57523.1 | ABB57296.1 | Synpcc7942_1493 | Synpcc7942_1266 | MazG family protein. | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.903 |
ABB57523.1 | ABB57522.1 | Synpcc7942_1493 | Synpcc7942_1492 | MazG family protein. | Conserved hypothetical protein. | 0.796 |
ABB57523.1 | ABB57861.1 | Synpcc7942_1493 | Synpcc7942_1831 | MazG family protein. | IMP dehydrogenase related 2. | 0.901 |
ABB57523.1 | era | Synpcc7942_1493 | Synpcc7942_0160 | MazG family protein. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.461 |
ABB57523.1 | gpmI | Synpcc7942_1493 | Synpcc7942_0469 | MazG family protein. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.613 |
ABB57523.1 | guaA | Synpcc7942_1493 | Synpcc7942_0189 | MazG family protein. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.901 |
ABB57523.1 | ndk | Synpcc7942_1493 | Synpcc7942_2497 | MazG family protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
ABB57523.1 | panC/cmk | Synpcc7942_1493 | Synpcc7942_1151 | MazG family protein. | Pantothenate synthetase / cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.464 |
ABB57523.1 | pheT | Synpcc7942_1493 | Synpcc7942_1293 | MazG family protein. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.450 |
ABB57523.1 | surE | Synpcc7942_1493 | Synpcc7942_2063 | MazG family protein. | Exopolyphosphatase / 5'-nucleotidase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.901 |
ABB57861.1 | ABB57296.1 | Synpcc7942_1831 | Synpcc7942_1266 | IMP dehydrogenase related 2. | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.945 |
ABB57861.1 | ABB57523.1 | Synpcc7942_1831 | Synpcc7942_1493 | IMP dehydrogenase related 2. | MazG family protein. | 0.901 |
ABB57861.1 | gpmI | Synpcc7942_1831 | Synpcc7942_0469 | IMP dehydrogenase related 2. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.404 |
ABB57861.1 | guaA | Synpcc7942_1831 | Synpcc7942_0189 | IMP dehydrogenase related 2. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.999 |