STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sasAHistidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (387 aa)    
Predicted Functional Partners:
ABB56127.1
Two component transcriptional regulator, winged helix family.
 
  0.994
kaiC
Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
    
 
 0.992
ABB57847.1
Response regulator receiver domain protein (CheY-like).
 
   0.976
ABB57890.1
Two component transcriptional regulator, LuxR family.
 
 
 0.930
ABB57483.1
Two component transcriptional regulator, winged helix family.
 
   0.929
ABB58446.1
Two component transcriptional regulator, winged helix family.
 
   0.907
ABB57759.1
Potassium-transporting ATPase D chain.
 
      0.900
ABB57673.1
Diguanylate cyclase with GAF sensor.
   
 0.885
ABB57845.1
Response regulator receiver domain protein (CheY-like).
 
 0.869
ABB57903.1
Two component transcriptional regulator, winged helix family.
 
   0.843
Your Current Organism:
Synechococcus elongatus
NCBI taxonomy Id: 1140
Other names: Anacystis nidulans R2, S. elongatus PCC 7942, Synechococcus elongatus PCC 7942, Synechococcus leopoliensis UTEX 2434, Synechococcus leopoliensis strain PCC 7942, Synechococcus sp. IAM M-200, Synechococcus sp. PCC 7942
Server load: low (30%) [HD]