Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Putative OxPP cycle protein OpcA; May be involved in the functional assembly of glucose 6- phosphate dehydrogenase (445 aa)
Predicted Functional Partners:
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone (511 aa)
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily (397 aa)
Fructose-1,6-bisphosphatase class 1; Catalyzes only the formation of fructose 6-phosphate by hydrolysis of fructose 1,6-bisphosphate; Belongs to the FBPase class 1 family (344 aa)
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH; Belongs to the 6-phosphogluconate dehydrogenase family (471 aa)