STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (256 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase (GK); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.972
PS3_2778
Proline iminopeptidase (PIP); Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
    
  0.904
proA
Gamma-glutamyl phosphate reductase (GPR); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.903
PS3_9200
Competence protein EC.
     
 0.647
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.630
PS3_6961
Alcohol acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.616
PS3_16592
Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
 
 0.568
PS3_6943
Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.525
PS3_11201
DNA-binding protein Dps; Belongs to the Dps family.
       0.505
fni
Isopentenyl diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
    
 0.460
Your Current Organism:
Lactobacillus gastricus
NCBI taxonomy Id: 1144300
Other names: L. gastricus PS3, Lactobacillus gastricus PS3, Lactobacillus gastricus str. PS3, Lactobacillus gastricus strain PS3
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