node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRADO0088 | BRADO0093 | BRADO0088 | BRADO0093 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.481 |
BRADO0088 | accD | BRADO0088 | BRADO0089 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | 0.898 |
BRADO0088 | ribD | BRADO0088 | BRADO4428 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.649 |
BRADO0088 | trpA | BRADO0088 | BRADO0090 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.710 |
BRADO0088 | trpB | BRADO0088 | BRADO0091 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.680 |
BRADO0088 | trpD | BRADO0088 | BRADO4109 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.467 |
BRADO0088 | trpE(G) | BRADO0088 | BRADO1991 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | Anthranilate synthase [Includes: Glutamine amidotransferase]; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.618 |
BRADO0088 | trpF | BRADO0088 | BRADO0092 | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | N-(5'-phosphoribosyl)anthranilate isomerase (PRAI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. | 0.729 |
BRADO0093 | BRADO0088 | BRADO0093 | BRADO0088 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | 0.481 |
BRADO0093 | accD | BRADO0093 | BRADO0089 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | 0.481 |
BRADO0093 | trpA | BRADO0093 | BRADO0090 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.618 |
BRADO0093 | trpB | BRADO0093 | BRADO0091 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.618 |
BRADO0093 | trpF | BRADO0093 | BRADO0092 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | N-(5'-phosphoribosyl)anthranilate isomerase (PRAI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. | 0.618 |
accD | BRADO0088 | BRADO0089 | BRADO0088 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | Putative folC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the folylpolyglutamate synthase family. | 0.898 |
accD | BRADO0093 | BRADO0089 | BRADO0093 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.481 |
accD | ribD | BRADO0089 | BRADO4428 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.466 |
accD | trpA | BRADO0089 | BRADO0090 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.691 |
accD | trpB | BRADO0089 | BRADO0091 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.691 |
accD | trpE(G) | BRADO0089 | BRADO1991 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | Anthranilate synthase [Includes: Glutamine amidotransferase]; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.534 |
accD | trpF | BRADO0089 | BRADO0092 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | N-(5'-phosphoribosyl)anthranilate isomerase (PRAI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. | 0.691 |