STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (322 aa)    
Predicted Functional Partners:
fumA
Fumarase A (fumarate hydratase class I); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.997
BRADO0613
Putative citrate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the citrate synthase family.
  
 0.991
BRADO0614
Putative citrate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the citrate synthase family.
  
 0.991
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 0.989
fumC
Fumarate hydratase class II (Fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.987
BRADO3367
Putative bifunctional enzyme: malic oxidoreductase (N-terminal); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.984
BRADO5322
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Function of strongly homologous gene; enzyme.
  
 0.971
icd
Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.961
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
 
 
 0.951
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.945
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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