node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRADO0084 | BRADO0796 | BRADO0084 | BRADO0796 | Putative helicase-exonuclease type V protein family, addA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.829 |
BRADO0084 | dnaN | BRADO0084 | BRADO0002 | Putative helicase-exonuclease type V protein family, addA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.552 |
BRADO0084 | polA | BRADO0084 | BRADO0752 | Putative helicase-exonuclease type V protein family, addA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.554 |
BRADO0084 | recQ | BRADO0084 | BRADO1125 | Putative helicase-exonuclease type V protein family, addA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase RecQ; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.465 |
BRADO0084 | truB | BRADO0084 | BRADO0055 | Putative helicase-exonuclease type V protein family, addA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.481 |
BRADO0084 | uvrD | BRADO0084 | BRADO5618 | Putative helicase-exonuclease type V protein family, addA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. | DNA helicase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.472 |
BRADO0671 | BRADO0796 | BRADO0671 | BRADO0796 | Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.446 |
BRADO0671 | dnaN | BRADO0671 | BRADO0002 | Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.782 |
BRADO0671 | polA | BRADO0671 | BRADO0752 | Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.728 |
BRADO0671 | recQ | BRADO0671 | BRADO1125 | Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATP-dependent DNA helicase RecQ; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.821 |
BRADO0671 | topA | BRADO0671 | BRADO4508 | Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.730 |
BRADO0671 | uvrD | BRADO0671 | BRADO5618 | Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA helicase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
BRADO0796 | BRADO0084 | BRADO0796 | BRADO0084 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Putative helicase-exonuclease type V protein family, addA subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the helicase family. UvrD subfamily. | 0.829 |
BRADO0796 | BRADO0671 | BRADO0796 | BRADO0671 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.446 |
BRADO0796 | BRADO0797 | BRADO0796 | BRADO0797 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Putative conjugal transfer protein, traC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.531 |
BRADO0796 | BRADO6209 | BRADO0796 | BRADO6209 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Putative Prophage CP4-57 regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.751 |
BRADO0796 | dnaN | BRADO0796 | BRADO0002 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.710 |
BRADO0796 | polA | BRADO0796 | BRADO0752 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.520 |
BRADO0796 | recQ | BRADO0796 | BRADO1125 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | ATP-dependent DNA helicase RecQ; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.599 |
BRADO0796 | topA | BRADO0796 | BRADO4508 | Putative Conjugal transfer protein, traA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.452 |