STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthetase (Biotin synthase); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa)    
Predicted Functional Partners:
BRADO4170
Putative Biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase), birA-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.945
BRADO6061
Putative aminotransferase protein, class-III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.851
BRADO2614
Aminotransferase class-III; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.843
hemA-3
5-aminolevulinate synthase (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase); Function of strongly homologous gene; enzyme.
  
 0.780
hemA-4
5-aminolevulinic acid synthase (ALAS); Function of strongly homologous gene; enzyme.
  
 0.780
hemA
5-aminolevulinic acid synthase (ALAS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.778
hemA-2
5-aminolevulinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.775
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.727
BRADO2423
Putative transcriptional regulatory protein, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
     0.640
thiG
Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.578
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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