node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRADO3157 | rplA | BRADO3157 | BRADO3049 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.963 |
BRADO3157 | rplD | BRADO3157 | BRADO3067 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.963 |
BRADO3157 | rpsA | BRADO3157 | BRADO0096 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.924 |
BRADO3157 | rpsB | BRADO3157 | BRADO4140 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 30S ribosomal protein S2; Function of homologous gene experimentally demonstrated in an other organism; RNA; Belongs to the universal ribosomal protein uS2 family. | 0.960 |
BRADO3157 | rpsK | BRADO3157 | BRADO3089 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.963 |
BRADO3157 | tig | BRADO3157 | BRADO4200 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Trigger factor (TF), molecular chaperone involved in cell division; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.759 |
BRADO3157 | tsf | BRADO3157 | BRADO4139 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.977 |
frr | pyrH | BRADO4137 | BRADO4138 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | 0.953 |
frr | rplA | BRADO4137 | BRADO3049 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.986 |
frr | rplD | BRADO4137 | BRADO3067 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal subunit protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.963 |
frr | rpsA | BRADO4137 | BRADO0096 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.626 |
frr | rpsB | BRADO4137 | BRADO4140 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 30S ribosomal protein S2; Function of homologous gene experimentally demonstrated in an other organism; RNA; Belongs to the universal ribosomal protein uS2 family. | 0.993 |
frr | rpsK | BRADO4137 | BRADO3089 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.976 |
frr | tig | BRADO4137 | BRADO4200 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Trigger factor (TF), molecular chaperone involved in cell division; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.885 |
frr | tsf | BRADO4137 | BRADO4139 | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.986 |
pyrH | frr | BRADO4138 | BRADO4137 | Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.953 |
pyrH | rplA | BRADO4138 | BRADO3049 | Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.893 |
pyrH | rpsB | BRADO4138 | BRADO4140 | Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | 30S ribosomal protein S2; Function of homologous gene experimentally demonstrated in an other organism; RNA; Belongs to the universal ribosomal protein uS2 family. | 0.939 |
pyrH | rpsK | BRADO4138 | BRADO3089 | Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.517 |
pyrH | tig | BRADO4138 | BRADO4200 | Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | Trigger factor (TF), molecular chaperone involved in cell division; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.735 |