STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfaEBifunctional protein RfaE (Involved in ADP-L-glycero-D-manno-heptose synthesis); Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (490 aa)    
Predicted Functional Partners:
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
 
 0.997
gmhA
Phosphoheptose isomerase (Sedoheptulose 7-phosphate isomerase); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.997
BRADO5205
Putative Histidinol-phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.989
BRADO5167
Putative Phosphoheptose isomerase (Sedoheptulose 7-phosphate isomerase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.981
rfaF
ADP-heptose--LPS heptosyltransferase II; Function of strongly homologous gene; enzyme.
 
  
 0.970
BRADO5200
Putative O-antigen ligase (RfaL-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
     
 0.940
BRADO5199
Putative polysaccharide biosynthesis protein (capD-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
       0.803
BRADO5168
Putative dTDP-glucose 4,6-dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.720
rfbB
dTDP-D-glucose 4,6-dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
     
 0.720
kpsF
Arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.638
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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