STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuA2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa)    
Predicted Functional Partners:
leuD-2
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.988
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.985
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.984
leuC-2
3-isopropylmalate dehydratase (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.984
ilvD
Dihydroxyacid dehydratase (DAD); Function of strongly homologous gene; enzyme; Belongs to the IlvD/Edd family.
 
 
 0.978
ilvD-3
Dihydroxy-acid dehydratase (DAD); Function of strongly homologous gene; enzyme; Belongs to the IlvD/Edd family.
 
 
 0.977
BRADO2489
Putative dihydroxy-acid dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the IlvD/Edd family.
 
 
 0.969
BRADO6039
Putative branched-chain amino acid aminotransferase protein (BCAT); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.968
BRADO6909
Putative branched-chain-amino-acid aminotransferase (Transaminase B) (BCAT); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.968
ilvD-2
Dihydroxyacid dehydratase (DAD); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family.
 
 
 0.964
Your Current Organism:
Bradyrhizobium sp. ORS278
NCBI taxonomy Id: 114615
Other names: B. sp. ORS 278, Bradyrhizobium sp. ORS 278
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