node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddlA | ddlB | BRADO2810 | BRADO5656 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.908 |
ddlA | ftsI | BRADO2810 | BRADO5665 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | Division-specific transpeptidase, penicillin-binding protein; Function of strongly homologous gene; enzyme. | 0.661 |
ddlA | ftsW | BRADO2810 | BRADO5660 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | Essential cell division protein (stabilizes FtsZ ring); Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the SEDS family. | 0.837 |
ddlA | mraY | BRADO2810 | BRADO5662 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.784 |
ddlA | murC | BRADO2810 | BRADO5658 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | UDP-N-acetyl-muramate:alanine ligase, L-alanine adding enzyme; Cell wall formation; Belongs to the MurCDEF family. | 0.984 |
ddlA | murD | BRADO2810 | BRADO5661 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.854 |
ddlA | murE | BRADO2810 | BRADO5664 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.806 |
ddlA | murF | BRADO2810 | BRADO5663 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.989 |
ddlA | murG | BRADO2810 | BRADO5659 | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.884 |
ddlB | ddlA | BRADO5656 | BRADO2810 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | 0.908 |
ddlB | ftsI | BRADO5656 | BRADO5665 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Division-specific transpeptidase, penicillin-binding protein; Function of strongly homologous gene; enzyme. | 0.755 |
ddlB | ftsW | BRADO5656 | BRADO5660 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Essential cell division protein (stabilizes FtsZ ring); Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the SEDS family. | 0.918 |
ddlB | mraY | BRADO5656 | BRADO5662 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.839 |
ddlB | murC | BRADO5656 | BRADO5658 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetyl-muramate:alanine ligase, L-alanine adding enzyme; Cell wall formation; Belongs to the MurCDEF family. | 0.975 |
ddlB | murD | BRADO5656 | BRADO5661 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.923 |
ddlB | murE | BRADO5656 | BRADO5664 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.893 |
ddlB | murF | BRADO5656 | BRADO5663 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.988 |
ddlB | murG | BRADO5656 | BRADO5659 | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.957 |
ftsI | ddlA | BRADO5665 | BRADO2810 | Division-specific transpeptidase, penicillin-binding protein; Function of strongly homologous gene; enzyme. | D-alanine--D-alanine ligase A (D-alanylalanine synthetase A) (D-Ala-D-Ala ligase A); Cell wall formation. | 0.661 |
ftsI | ddlB | BRADO5665 | BRADO5656 | Division-specific transpeptidase, penicillin-binding protein; Function of strongly homologous gene; enzyme. | D-alanine-D-alanine ligase, affects cell division; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.755 |