node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | gene:10498871 | gene:10497505 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.964 |
apt | guaA | gene:10498871 | gene:10499709 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.995 |
apt | ndkR | gene:10498871 | gene:10499478 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.422 |
apt | sll1108 | gene:10498871 | gene:10500600 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.910 |
gmk | apt | gene:10497505 | gene:10498871 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.964 |
gmk | guaA | gene:10497505 | gene:10499709 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.960 |
gmk | ndkR | gene:10497505 | gene:10499478 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.938 |
gmk | nrdA | gene:10497505 | gene:10499210 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.919 |
gmk | pykF | gene:10497505 | gene:10498441 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; ORF_ID:sll1275; In the C-terminal section; belongs to the PEP-utilizing enzyme family. | 0.940 |
gmk | pykF-2 | gene:10497505 | gene:10500125 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; ORF_ID:sll0587. | 0.915 |
gmk | sll1033 | gene:10497505 | gene:10497627 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | ORF_ID:sll1033; unknown protein. | 0.939 |
gmk | sll1108 | gene:10497505 | gene:10500600 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
gmk | spoT | gene:10497505 | gene:10498949 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | (p)ppGpp 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into GDP. It may also be capable of catalyzing the synthesis of ppGpp (By similarity); Belongs to the RelA/SpoT family. | 0.920 |
gmk | ssl2982 | gene:10497505 | gene:10499322 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.953 |
guaA | apt | gene:10499709 | gene:10498871 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.995 |
guaA | gmk | gene:10499709 | gene:10497505 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.960 |
guaA | ndkR | gene:10499709 | gene:10499478 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.838 |
guaA | nrdA | gene:10499709 | gene:10499210 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Ribonucleotide reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.627 |
guaA | pykF | gene:10499709 | gene:10498441 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Pyruvate kinase; ORF_ID:sll1275; In the C-terminal section; belongs to the PEP-utilizing enzyme family. | 0.669 |
guaA | sll1108 | gene:10499709 | gene:10500600 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.971 |