node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hypB | ureA | gene:10498159 | gene:10498718 | Hydrogenase expression/formation protein; ORF_ID:sll1079. | Urease gamma subunit; ORF_ID:slr1256; Belongs to the urease gamma subunit family. | 0.642 |
hypB | ureB | gene:10498159 | gene:10499364 | Hydrogenase expression/formation protein; ORF_ID:sll1079. | Urease beta subunit; ORF_ID:sll0420; Belongs to the urease beta subunit family. | 0.685 |
hypB | ureC | gene:10498159 | gene:10497944 | Hydrogenase expression/formation protein; ORF_ID:sll1079. | Urease alpha subunit; ORF_ID:sll1750; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. | 0.642 |
hypB | ureD | gene:10498159 | gene:10497929 | Hydrogenase expression/formation protein; ORF_ID:sll1079. | Urease accessory protein D; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.897 |
hypB | ureE | gene:10498159 | gene:10498367 | Hydrogenase expression/formation protein; ORF_ID:sll1079. | Urease accessory protein E; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.979 |
hypB | ureF | gene:10498159 | gene:10498220 | Hydrogenase expression/formation protein; ORF_ID:sll1079. | Urease accessory protein F; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.975 |
hypB | ureG | gene:10498159 | gene:10497833 | Hydrogenase expression/formation protein; ORF_ID:sll1079. | Urease accessory protein G; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.430 |
hypB-2 | ureA | gene:10499188 | gene:10498718 | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | Urease gamma subunit; ORF_ID:slr1256; Belongs to the urease gamma subunit family. | 0.642 |
hypB-2 | ureB | gene:10499188 | gene:10499364 | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | Urease beta subunit; ORF_ID:sll0420; Belongs to the urease beta subunit family. | 0.680 |
hypB-2 | ureC | gene:10499188 | gene:10497944 | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | Urease alpha subunit; ORF_ID:sll1750; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. | 0.642 |
hypB-2 | ureD | gene:10499188 | gene:10497929 | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | Urease accessory protein D; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.895 |
hypB-2 | ureE | gene:10499188 | gene:10498367 | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | Urease accessory protein E; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.967 |
hypB-2 | ureF | gene:10499188 | gene:10498220 | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | Urease accessory protein F; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.973 |
hypB-2 | ureG | gene:10499188 | gene:10497833 | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | Urease accessory protein G; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.855 |
sll1749 | sll1751 | gene:10497945 | gene:10497943 | ORF_ID:sll1749; hypothetical protein. | ORF_ID:sll1751; unknown protein. | 0.490 |
sll1749 | ureC | gene:10497945 | gene:10497944 | ORF_ID:sll1749; hypothetical protein. | Urease alpha subunit; ORF_ID:sll1750; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. | 0.732 |
sll1751 | sll1749 | gene:10497943 | gene:10497945 | ORF_ID:sll1751; unknown protein. | ORF_ID:sll1749; hypothetical protein. | 0.490 |
sll1751 | ureC | gene:10497943 | gene:10497944 | ORF_ID:sll1751; unknown protein. | Urease alpha subunit; ORF_ID:sll1750; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. | 0.515 |
ureA | hypB | gene:10498718 | gene:10498159 | Urease gamma subunit; ORF_ID:slr1256; Belongs to the urease gamma subunit family. | Hydrogenase expression/formation protein; ORF_ID:sll1079. | 0.642 |
ureA | hypB-2 | gene:10498718 | gene:10499188 | Urease gamma subunit; ORF_ID:slr1256; Belongs to the urease gamma subunit family. | Hydrogenase isoenzymes formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | 0.642 |