node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arsC | grxC | gene:10499283 | gene:10498397 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | 0.703 |
arsC | slr0303 | gene:10499283 | gene:10500174 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | ORF_ID:slr0303; unknown protein. | 0.840 |
arsC | trxA | gene:10499283 | gene:10498154 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Thioredoxin; ORF_ID:slr1139; gene:trxA or trx. | 0.889 |
arsC | trxA-3 | gene:10499283 | gene:10500127 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Thioredoxin; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.886 |
grxC | arsC | gene:10498397 | gene:10499283 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.703 |
grxC | gshB | gene:10498397 | gene:10498398 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Glutathione synthetase; ORF_ID:slr1238. | 0.714 |
grxC | msrA | gene:10498397 | gene:10497479 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). | 0.620 |
grxC | nrdA | gene:10498397 | gene:10499210 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Ribonucleotide reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | 0.859 |
grxC | sll0755 | gene:10498397 | gene:10499629 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Thiol-specific antioxidant protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.622 |
grxC | slr0303 | gene:10498397 | gene:10500174 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | ORF_ID:slr0303; unknown protein. | 0.675 |
grxC | slr0600 | gene:10498397 | gene:10500638 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | ORF_ID:slr0600; unknown protein. | 0.733 |
grxC | slr1846 | gene:10498397 | gene:10497939 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Uncharacterized monothiol glutaredoxin ycf64-like; ORF_ID:slr1846; hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.670 |
grxC | trxA | gene:10498397 | gene:10498154 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Thioredoxin; ORF_ID:slr1139; gene:trxA or trx. | 0.572 |
grxC | trxA-3 | gene:10498397 | gene:10500127 | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | Thioredoxin; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0.692 |
gshB | grxC | gene:10498398 | gene:10498397 | Glutathione synthetase; ORF_ID:slr1238. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | 0.714 |
gshB | slr1846 | gene:10498398 | gene:10497939 | Glutathione synthetase; ORF_ID:slr1238. | Uncharacterized monothiol glutaredoxin ycf64-like; ORF_ID:slr1846; hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.641 |
msrA | grxC | gene:10497479 | gene:10498397 | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | 0.620 |
nrdA | grxC | gene:10499210 | gene:10498397 | Ribonucleotide reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | 0.859 |
sll0755 | grxC | gene:10499629 | gene:10498397 | Thiol-specific antioxidant protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity); Belongs to the glutaredoxin family. | 0.622 |
sll0755 | slr0600 | gene:10499629 | gene:10500638 | Thiol-specific antioxidant protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | ORF_ID:slr0600; unknown protein. | 0.918 |