node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | gene:10500466 | gene:10499904 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | 0.999 |
carA | pyrB | gene:10500466 | gene:10499127 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Aspartate carbamoyltransferase; ORF_ID:slr1476; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | gene:10500466 | gene:10497811 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Dihydroorotase; Non-functional DHOase. | 0.980 |
carA | pyrC-2 | gene:10500466 | gene:10499421 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.630 |
carA | pyrD | gene:10500466 | gene:10500392 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.861 |
carA | pyrF | gene:10500466 | gene:10498681 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.949 |
carA | pyrR | gene:10500466 | gene:10499906 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.840 |
carA | slr1616 | gene:10500466 | gene:10497770 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | ORF_ID:slr1616; unknown protein. | 0.996 |
carA | umpS | gene:10500466 | gene:10499569 | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | Uridine 5'-monophosphate synthase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.950 |
carB | carA | gene:10499904 | gene:10500466 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Carbamoyl-phosphate synthetase subunit A; ORF_ID:sll1498; gene:carA or pyrA; Belongs to the CarA family. | 0.999 |
carB | purA | gene:10499904 | gene:10498181 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.545 |
carB | pyrB | gene:10499904 | gene:10499127 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Aspartate carbamoyltransferase; ORF_ID:slr1476; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | gene:10499904 | gene:10497811 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Dihydroorotase; Non-functional DHOase. | 0.926 |
carB | pyrC-2 | gene:10499904 | gene:10499421 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.590 |
carB | pyrD | gene:10499904 | gene:10500392 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.873 |
carB | pyrF | gene:10499904 | gene:10498681 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.879 |
carB | pyrR | gene:10499904 | gene:10499906 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.944 |
carB | slr1616 | gene:10499904 | gene:10497770 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | ORF_ID:slr1616; unknown protein. | 0.900 |
carB | umpS | gene:10499904 | gene:10499569 | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | Uridine 5'-monophosphate synthase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.923 |
purA | carB | gene:10498181 | gene:10499904 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Carbamoyl-phosphate synthase, pyrimidine-specific, large chain; ORF_ID:sll0370; gene:carB or pyrA. | 0.545 |