STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slr0942Aldehyde reductase; Aldo/keto reductase with broad substrate spectrum. Catalyzes the NADPH-dependent reduction of aldehyde- and ketone-groups of different classes of carbonyl compounds to the corresponding alcohols. Highest enzymatic efficiency is observed with 4-oxonon-2-enal (4-ONE) and 4-hydroxynon-2-enal (4-HNE), that are lipid peroxidation products, and 9,10-phenanthrenequinone (9,10-PQ), a photoproduct of phenanthrene that is one of the most prevalent polycyclic aromatic hydrocarbons in the environment. Is also active on sugar-derived reactive carbonyls such as methylglyoxal (MG) [...] (327 aa)    
Predicted Functional Partners:
sll0990
Formaldehyde dehydrogenase (glutathione); ORF_ID:sll0990; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 
 0.994
slr1192
Zinc-containing alcohol dehydrogenase family; ORF_ID:slr1192.
  
 
 0.993
slr0091
Aldehyde dehydrogenase; ORF_ID:slr0091; Belongs to the aldehyde dehydrogenase family.
 
 
 0.982
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.922
gldA
Glycerol dehydrogenase; ORF_ID:slr1167.
     
  0.900
slr0315
ORF_ID:slr0315; hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.899
slr1503
ORF_ID:slr1503; unknown protein.
 
 
 0.851
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
   
 0.800
HAGH1
Glyoxalase II; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
   
  
 0.735
slr0086
ORF_ID:slr0086; unknown protein; Belongs to the heat shock protein 70 family.
      
 0.693
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B
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