node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroB | arsA | gene:10498939 | gene:10498731 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Arsenical resistance operon repressor; ORF_ID:sll1957. | 0.629 |
aroB | slr0944 | gene:10498939 | gene:10499281 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Uncharacterized transporter slr0944; ORF_ID:slr0944; hypothetical protein. | 0.439 |
arsA | aroB | gene:10498731 | gene:10498939 | Arsenical resistance operon repressor; ORF_ID:sll1957. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.629 |
arsA | arsC | gene:10498731 | gene:10499283 | Arsenical resistance operon repressor; ORF_ID:sll1957. | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.418 |
arsA | slr0944 | gene:10498731 | gene:10499281 | Arsenical resistance operon repressor; ORF_ID:sll1957. | Uncharacterized transporter slr0944; ORF_ID:slr0944; hypothetical protein. | 0.940 |
arsA | slr0945 | gene:10498731 | gene:10499282 | Arsenical resistance operon repressor; ORF_ID:sll1957. | NADPH-dependent quinone reductase ArsH; Has high NADPH-dependent quinone reductase activity with a preference for quinones with hydrophobic substituents. Reduces also CrO4(2-) and Fe(3+). Somewhat active with NADH. May be involved in response to oxidative stress caused by arsenic. | 0.525 |
arsC | arsA | gene:10499283 | gene:10498731 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Arsenical resistance operon repressor; ORF_ID:sll1957. | 0.418 |
arsC | grxC-2 | gene:10499283 | gene:10500473 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). | 0.834 |
arsC | sll0914 | gene:10499283 | gene:10499280 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | ORF_ID:sll0914; unknown protein. | 0.644 |
arsC | slr0303 | gene:10499283 | gene:10500174 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | ORF_ID:slr0303; unknown protein. | 0.840 |
arsC | slr0944 | gene:10499283 | gene:10499281 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Uncharacterized transporter slr0944; ORF_ID:slr0944; hypothetical protein. | 0.981 |
arsC | slr0945 | gene:10499283 | gene:10499282 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | NADPH-dependent quinone reductase ArsH; Has high NADPH-dependent quinone reductase activity with a preference for quinones with hydrophobic substituents. Reduces also CrO4(2-) and Fe(3+). Somewhat active with NADH. May be involved in response to oxidative stress caused by arsenic. | 0.963 |
arsC | slr0948 | gene:10499283 | gene:10499285 | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | ORF_ID:slr0948; unknown protein. | 0.774 |
grxC-2 | arsC | gene:10500473 | gene:10499283 | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.834 |
grxC-2 | slr0303 | gene:10500473 | gene:10500174 | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). | ORF_ID:slr0303; unknown protein. | 0.546 |
grxC-2 | slr0944 | gene:10500473 | gene:10499281 | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). | Uncharacterized transporter slr0944; ORF_ID:slr0944; hypothetical protein. | 0.547 |
grxC-2 | slr0945 | gene:10500473 | gene:10499282 | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins (By similarity). | NADPH-dependent quinone reductase ArsH; Has high NADPH-dependent quinone reductase activity with a preference for quinones with hydrophobic substituents. Reduces also CrO4(2-) and Fe(3+). Somewhat active with NADH. May be involved in response to oxidative stress caused by arsenic. | 0.555 |
merA | slr0303 | gene:10497942 | gene:10500174 | Mercuric reductase; ORF_ID:slr1849. | ORF_ID:slr0303; unknown protein. | 0.464 |
merA | slr0944 | gene:10497942 | gene:10499281 | Mercuric reductase; ORF_ID:slr1849. | Uncharacterized transporter slr0944; ORF_ID:slr0944; hypothetical protein. | 0.437 |
sll0914 | arsC | gene:10499280 | gene:10499283 | ORF_ID:sll0914; unknown protein. | Arsenate reductase; Reduces arsenate [As(V)] to arsenite [As(III)] using glutathione and glutaredoxin as sources of reducing equivalents. GrxA is the most effective electron donor in vivo compared to other glutaredoxins. Constitutes the major arsenate reductase compared to ArsI1 and ArsI2. Also shows weak phosphatase activity toward p- nitrophenyl phosphate; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.644 |